Slideshow

<a href="https://lsi.sites.olt.ubc.ca/2011/01/12/novel-matrix-metalloproteinase-inhibitor-18fmarimastat-aryltrifluoroborate-as-a-probe-for-in-vivo-positron-emission-tomography-imaging-in-cancer/" title="Overall Lab:"><img src="https://lsi.sites.olt.ubc.ca/files/2011/01/Overall-spotlight-72RGB-150x150.jpg" alt="Overall Lab:" class="thumbnail thumbnail " /></a>

Overall Lab:

Novel Matrix Metalloproteinase Inhibitor [18F]Marimastat-Aryltrifluoroborate as a Probe for In vivo Positron Emission Tomography Imaging in Cancer.

<a href="https://lsi.sites.olt.ubc.ca/2011/01/12/the-n-terminal-disease-hot-spot-of-ryanodine-receptors-forms-a-cytoplasmic-vestibule/" title="Van Petegem Lab:"><img src="https://lsi.sites.olt.ubc.ca/files/2011/01/Van-Petegem-spotlight-150x150.jpg" alt="Van Petegem Lab:" class="thumbnail thumbnail " /></a>

Van Petegem Lab:

The N-terminal disease hot spot of ryanodine receptors forms a cytoplasmic vestibule.

<a href="https://lsi.sites.olt.ubc.ca/2011/01/12/origins-and-evolution-of-antibiotic-resistance/" title="Davies Lab:"><img src="https://lsi.sites.olt.ubc.ca/files/2011/01/Davies-spotlight-150x150.jpg" alt="Davies Lab:" class="thumbnail thumbnail " /></a>

Davies Lab:

Origins and Evolution of Antibiotic Resistance

<a href="https://lsi.sites.olt.ubc.ca/2011/01/12/lipid-serves-as-cells-built-in-ph-sensor/" title="Loewen Lab:"><img src="https://lsi.sites.olt.ubc.ca/files/2011/01/Chris-Loewen-spotlight-150x150.jpg" alt="Loewen Lab:" class="thumbnail thumbnail " /></a>

Loewen Lab:

Lipid serves as cells’ built-in pH sensor

<a href="https://lsi.sites.olt.ubc.ca/2011/01/12/overall-lab-3/" title="Overall Lab:"><img src="https://lsi.sites.olt.ubc.ca/files/2011/01/nmeth.1467-F1-150x150.jpg" alt="Overall Lab:" class="thumbnail thumbnail " /></a>

Overall Lab:

Enrichment of protein carboxy-terminal peptides by negative selection. Chemical modification of free amino- and carboxy-groups before tryptic digest allows selective polymer-based removal of protein internal peptides. This new method provides access to protein carboxy-termini on a system-wide scale, enabling analysis of proteolytic processing and other modifications at protein carboxy-termini in health and disease.

<a href="https://lsi.sites.olt.ubc.ca/2011/01/12/moerman-lab-4/" title="Moerman Lab:"><img src="https://lsi.sites.olt.ubc.ca/files/2011/01/Cover-Moerman-June2010-copy-150x150.png" alt="Moerman Lab:" class="thumbnail thumbnail " /></a>

Moerman Lab:

Whole-Genome Profiling of Mutagenesis in Caenorhabditis elegans

<a href="https://lsi.sites.olt.ubc.ca/2011/01/12/nabi-lab/" title="Nabi Lab:"><img src="https://lsi.sites.olt.ubc.ca/files/2011/01/image-for-spotlight3-150x150.jpg" alt="Nabi Lab:" class="thumbnail thumbnail " /></a>

Nabi Lab:

Pseudopodial actin dynamics control epithelial-mesenchymal transition in metastatic cancer cells.

<a href="https://lsi.sites.olt.ubc.ca/2011/01/12/gold-roskelley-lab/" title="Gold & Roskelley Lab:"><img src="https://lsi.sites.olt.ubc.ca/files/2011/01/Spencer1-150x150.jpg" alt="Gold & Roskelley Lab:" class="thumbnail thumbnail " /></a>

Gold & Roskelley Lab:

Preventing the Activation or Cycling of the Rap1 GTPase Alters Adhesion and Cytoskeletal Dynamics and Blocks Metastatic Melanoma Cell Extravasation into the lungs.

<a href="https://lsi.sites.olt.ubc.ca/2011/01/12/mcintosh-lab/" title="L. McIntosh Lab:"><img src="https://lsi.sites.olt.ubc.ca/files/2011/01/image-for-spotlight5-150x150.jpg" alt="L. McIntosh Lab:" class="thumbnail thumbnail " /></a>

L. McIntosh Lab:

Ras signal requires dynamic properties of Ets1 for phosphorylation-enhanced binding to co-activator CBP

<a href="https://lsi.sites.olt.ubc.ca/2011/01/12/danny-leung/" title="Lorincz Lab:"><img src="https://lsi.sites.olt.ubc.ca/files/2011/01/Danny-150x150.jpg" alt="Lorincz Lab:" class="thumbnail thumbnail " /></a>

Lorincz Lab:

UBC graduate student, Danny Leung, finds ‘start/stop switch’ for retroviruses