Autocrine motility factor/phosphoglucose isomerase regulates ER stress and cell death through control of ER calcium release
Authors: Min Fu, Lei Li, Tobias Albrecht, James D. Johnson, Liliana D. Kojic and Ivan R. Nabi. Lab of Robert Nabi, Cell and Developmental Biology Research Group, Department of Cellular & Physiological Sciences
Published in Cell Death and Differentiation (2011) 18, 1057–1070; doi:10.1038/cdd.2010.181
Abstract: This study showed autocrine motility factor/phosphoglucose isomerase (AMF/PGI) promotes cell survival towards ER stress by regulating ER Ca2+ release, identifying novel roles for these cancer-associated proteins in promoting tumor cell survival.
